VOL-4 ISSUE-4, October 2020

Medicinal properties of a naturally occurring pentacyclic dihydroxy triterpenoid uvaol

Pages : 11-15

Author(s) : Subrata Ghorai

Category : Review Paper

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Abstract :
Uvaol is a 6-6-6-6-6 pentacyclic ursane type dihydroxy triterpenoid. It is present in various plants such as Plumeria rubra, Olea europaea, Nerium oleander and Malus domestica. One step conversion of ursolic acid, a 6-6-6-6-6 pentacyclic triterpenic acid having an identical triterpenoid backbone, to uvaol has also been reported. A variety of pharmaceutical properties, including antimicrobial, hepatoprotective, anti-inflammatory, anti-tumour, anti-cancer, cardiovascular effects and healing of cutaneous wounds etc. have been reported. In this review, various plant sources of uvaol and its pharmaceutical properties have been reported.

Keywords : Plumeria rubra, Olea europaea, Nerium oleander, Malus domestica, uvaol, medicinal properties