VOL-1 ISSUE-1, April 2017

Nanotechnology in psoriasis

Pages : 48-53

Author(s) : Voshavar Chandrashekhar, Srujan Marepally*

Category : Review Paper

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Abstract :
Psoriasis is a chronic autoimmune skin disease with a substantial negative impact on the patient’s quality of life. To date, a wide range of treatment options such as topical delivery of corticosteroids, vitamin D derivatives, phototherapy, and administration of immuno-modulators are available. However, these approaches have major limitations such as a plethora of side effects and skin develops resistance to treatments over time. In addition, therapeutic outcome of psoriasis treatments also can be unpredictable. To address these limitations several attempts have been made in recent years using nanotechnology. These nanotherapeutics offer several advantages including reducing non specific targeting, bypassing first passage metabolism, increasing the efficacy of the drugs. However, there are no long-term effective therapies till today, so this remains at the top of the list for unmet needs.

Keywords : Psoriasis, autoimmune disease, nanotechnology